Pre-implantation genetic diagnosis (PGD) is a laboratory procedure used in conjunction with in vitro fertilization (IVF) to reduce the risk of passing on inherited conditions. Some of the most common reasons for PGD are specific single-gene conditions (such as cystic fibrosis or sickle cell anemia) and structural changes of a parent’s chromosomes. Families may also use PGD when a member of the family needs a bone marrow donor, as a way to have a child who can provide matching stem cells.
;”>Typically, couples in need of these techniques are not infertile but have a family history of a condition and want to reduce the risk of having another child with significant health issues or early death. Through generally available genetic screening, however, occasionally couples who are seeking fertility treatment are found to be at risk of passing on an inherited condition, and PGD may be an option for them.